Characterization of drug-neutralizing antibodies in patients with Fabry disease during infusion
M Lenders, B Schmitz, SM Brand, D Foell… - Journal of Allergy and …, 2018 - jacionline.org
FIG 1. Acute effect of ERT on antibody titers during infusion. Patients' inhibition profiles per
microgram purified total IgG before (pre) and directly after (post) infusion. A, Patient 1 (53d
infusion with agalsidase-a [14 mg]; body weight [BW]: 72 kg, infusion length: 60 minutes). B,
Patient 4 (98th infusion with agalsidase-a [14 mg]; BW: 82 kg, infusion length: 60 minutes).
C, Patient 10 (8th infusion with agalsidase-b [55 mg]; BW: 58 kg, infusion length: 240
minutes). D, Patient 16 (12th infusion with agalsidase-b [70 mg]; BW: 60.0 kg, infusion …
microgram purified total IgG before (pre) and directly after (post) infusion. A, Patient 1 (53d
infusion with agalsidase-a [14 mg]; body weight [BW]: 72 kg, infusion length: 60 minutes). B,
Patient 4 (98th infusion with agalsidase-a [14 mg]; BW: 82 kg, infusion length: 60 minutes).
C, Patient 10 (8th infusion with agalsidase-b [55 mg]; BW: 58 kg, infusion length: 240
minutes). D, Patient 16 (12th infusion with agalsidase-b [70 mg]; BW: 60.0 kg, infusion …