[HTML][HTML] Integrated bioinformatics analysis reveals key candidate genes and cytokine pathways involved in COVID-19 after rhinovirus infection in asthma patients
W Dai, D Cao, W Zhang, Y Wei, D Ding… - … Medical Journal of …, 2020 - ncbi.nlm.nih.gov
W Dai, D Cao, W Zhang, Y Wei, D Ding, B Li, Y Gao, L Zhao, Y Jiang, X Kong
Medical Science Monitor: International Medical Journal of Experimental …, 2020•ncbi.nlm.nih.govBackground Rhinovirus (RV) is the most common pathogen involved in asthma, and COVID-
19, caused by SARS-COV-2, may be more severe in asthma patients. Here, we applied
integrated bioinformatics to identify potential key genes and cytokine pathways after RV
infection in asthma, and analyzed changes in angiotensin-converting enzyme 2 (ACE2), the
cellular receptor of SARS-COV-2.
19, caused by SARS-COV-2, may be more severe in asthma patients. Here, we applied
integrated bioinformatics to identify potential key genes and cytokine pathways after RV
infection in asthma, and analyzed changes in angiotensin-converting enzyme 2 (ACE2), the
cellular receptor of SARS-COV-2.
Abstract
Background
Rhinovirus (RV) is the most common pathogen involved in asthma, and COVID-19, caused by SARS-COV-2, may be more severe in asthma patients. Here, we applied integrated bioinformatics to identify potential key genes and cytokine pathways after RV infection in asthma, and analyzed changes in angiotensin-converting enzyme 2 (ACE2), the cellular receptor of SARS-COV-2.
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