[HTML][HTML] Perturbation of a very late step of regulated exocytosis by a secretory carrier membrane protein (SCAMP2)-derived peptide
Z Guo, L Liu, D Cafiso, D Castle - Journal of Biological Chemistry, 2002 - ASBMB
Secretory carrier membrane proteins (SCAMPs) are conserved four transmembrane-
spanning proteins associated with recycling vesicular carriers. In mast cells, as in other cell
types, SCAMPs 1 and 2 are present in secretory granule membranes and other intracellular
membranes. We now demonstrate a population of these SCAMPs in plasma membranes.
Although small, this population partially colocalizes with SNARE proteins SNAP-23 and
syntaxin 4. A fraction of SCAMPs 1 and 2 also coimmunoprecipitates with SNAP-23. An …
spanning proteins associated with recycling vesicular carriers. In mast cells, as in other cell
types, SCAMPs 1 and 2 are present in secretory granule membranes and other intracellular
membranes. We now demonstrate a population of these SCAMPs in plasma membranes.
Although small, this population partially colocalizes with SNARE proteins SNAP-23 and
syntaxin 4. A fraction of SCAMPs 1 and 2 also coimmunoprecipitates with SNAP-23. An …
